Cancer drugs to stop heart failure
Experimental cancer drugs may also help prevent the development of a common cause of heart failure. Cardiac hypertrophy - enlargement of the heart muscle - can be deadly. Animal studies by researchers at the University of Pennsylvania showed enlargement of the cells by HDAC inhibitors are blocked. The study is published in the Journal of Clinical Investigation. Heart cells grow well as any other muscle-conditioning - cardiac hypertrophy, a sane response to exercise and training.It can, however, because of an unhealthy cardiovascular system or a genetic defect, in which case it can be dangerous. This is because the cardiovascular system must work harder to push blood through the heart, as to reduce the enlarged tissue space, must pass through them. few treatments lead
researcher Jonathan Epstein said: Despite the fact that this is a common problem for doctors and patients, we have very few, if appropriate, the drugs that stop the cellular processes that address this deterioration.These HDAC inhibitors could be among the first drugs that prevent known cardiac hypertrophy. The new research is based on the theory that some cases of hypertrophy by the overproduction of the protein caused Hop based. Hop is thought to control the growth of heart cells. E rich in fetuses and infants, but not normal adult. However, it seems that some people a higher normal protein that can lead to greater growth in cardiac muscle cells. The researchers believe that the DHAC inhibitors by blocking the chain of chemical reactions that work finally renewed cellgrowth triggers.