Blocking selected neurotransmitter activity in the decline in alcohol consumption
Contact: Clyde W. Hodge, Ph.D. - Chodgemed.unc.edu 919-843-4823 University of North Carolina at Chapel Hill, contact: Subhash C. Pandey, Ph.D. - Scpandeyuic.edu 312-569-7418 University of Illinois at Chicago Alcoholism: Clinical Experimental Research neuropeptide Y (NPY) is a neurotransmitter that is part of neurobiological functions, such as anxiety, pain, memory and feeding behavior. The researchers found that a compound that blocks NPY reduces the activity in the development and use of alcohol.These findings have important implications for the addiction treatment of alcohol abuse and. Peptides are a class of neurotransmitters, chemicals used by brain cells to communicate. Neuropeptide Y (NPY) peptide is the most common and widespread and is involved in a variety of
neurobiological functions, including anxiety, pain, memory and feeding behavior. Although previous animal research NPY systems in alcohol abuse and alcoholism, the results in the December issue of Alcoholism published involved has: Clinical and Experimental Research are shown for the first time that the connection is blocked NPY activity may be useful for the treatment of alcohol.NPY is the most powerful stimulant known feeding behavior, said Clyde W. Hodge, associate professor in the departments of psychiatry and pharmacology at the University of North Carolina at Chapel Hill and corresponding author of the study. For example, the brain region in the primary control of the food involved in the hypothalamus. Animal studies have shown that repeated treatment with
hypothalamic NPY produces obesity diet of normal rats. We suspect that alcohol may brain systems that perform other functions such as eating developed to scramble, because these neural systems developed long before humans discovered alcoholic beverages.The abuse of alcohol and drugs, therefore, can be considered disorders of consumption.Since NPY is a signal molecule, which produces its effects through different NPY receptors
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